Photoprotective and photorepair action of marine angiosperm extracts, Thalassia testudinum Banks ex König (Hyrocharitacea) and Syringodium filiforme Kützing (Cymodoceaceae)
DOI:
https://doi.org/10.15359/revmar.8-1.4Keywords:
Thalassia, Syringodium, radiation, photoprotection, skinAbstract
Previous studies with the aqueous-ethanol extracts obtained from the marine angiosperms T. testudinum and S. filiforme have shown their high polyphenolic content and marked antioxidant capacity. This study describes the effects of the topical application of the aqueous-ethanol extracts of T. testudinum and S. filiforme leaves against acute UVB-induced damage. The phanerogams used were collected 3-4m deep in La Habana’s northwestern coast. Five experimental groups were created for the administration of the treatment. The effect was evaluated in in vivo assays, radiating the skin of the dorsal region of albino mice with UVB (dose: 1.21x103 Jxcm2) for six minutes. Before or after UVB irradiation, animals received topical treatment with the extracts at doses of both angiosperms 500μg x cm2 on their skin. Significant differences were observed (P ≤ 0.05) between groups: T. testudinum, S. filiforme, irradiated subjects, and “placebo”. T. testudinum and S. filiforme extracts reduce macroscopic damage caused by UVB radiation in irradiated skins on preventive and photodamage models. In addition, these extracts show protective and repair effects against UVB radiation damage, which could be related to their antioxidant action.References
Aneiros, A. A., Concepción, A. R., Arteaga, S., Fundora, M. D., Fernández, A., Mata, M., … & Rodríguez, M. (2003). Extracto de planta marina con actividad antienvejecimiento, antiinflamatoria y analgésica, su obtención y formulaciones que lo contienen. No 22931. Habana, Cuba: Oficina Cubana de la Propiedad Industrial.
Bickers, R. D. (2004). Photosensitivity and others reactions to light. In McGraw-Hil (Eds.), Harrison’s Principles of Internal Medicine (pp. 324-329). New York, EE. UU.: McGraw-Hill.
Choquenet, B., Couteau, C., Paparis, E. & Coiffard, L. J. M. (2008). Quercetin and Rutin as Potential Sunscreen Agents: Determination of Efficacy by an in Vitro Method. J. Nat. Prod., 71, 1117-1118. http://dx.doi.org/10.1021/np7007297
Fisher, G., Quan, T., Purohit, J. T., Shao, Y., Cho, M. K., He, T., ... & Voorhees, J. J. (2009). Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin. Am. J. Pathol., 23, 101-114. http://dx.doi.org/10.2353/ajpath.2009.080599
González, K., Valdés-Iglesias, O., Laguna, A., Díaz, M. & González, J. (2011). Efecto antioxidante y contenido polifenólico de Syringodium filiforme (Cymodoceaceae). Rev. Biol Trop., 59(1), 465-472.
Karol, M. H. (2009). How environmental agents influence the aging process. Biomol. Ther., 17, 113-124. http://dx.doi.org/10.4062/biomolther.2009.17.2.113
Liou, T. G. & Campbell, E. J. (1995). Nonisotropic enzyme--inhibitor interactions: a novel nonoxidative mechanism for quantum proteolysis by human neutrophils. Biochemistry, 34, 16171-16177. http://dx.doi.org/10.1021/bi00049a032
Mc Milan, C. & Zapata, O. (1980). Sulphated phenolic compounds in seagrasses. Aquatic. Bot., 8, 267-278. http://dx.doi.org/10.1016/0304-3770(80)90055-8
Mora, M., Olivares, A. R., González, T. & Castro, M. I. (2010). El sol: ¿enemigo de nuestra piel? Medisan, 14, 525-537.
Narayanan, D. L., Saladi, R. N. & Fox, J. L. (2010). Ultraviolet radiation and skin cancer. Int. J. Dermatol., 49, 978-986. http://dx.doi.org/10.1111/j.1365-4632.2010.04474.x
Nussier, G., Rezzonico, B. & Grignon-Dubois, M. (2010). Chiroquid acid from Syringodium filiforme. Food. Chem., 120, 783-788. http://dx.doi.org/10.1016/j.foodchem.2009.11.010
Regalado, E. L., Roberto, M., Valdés, O., Morales, R. A., Laguna, A., Thomas, O. P., ... & Kijoad, A. (2012). Phytoquimical Analysis and Antioxidant Capacity of BM-21 a Bioactive Extract Rich in Polyphenolic Metabolites From de Sea Grass Thalassia testudinum. Mar. Biotechnol., 7, 47-50.
Regalado, E. L., Rodríguez, M., Menéndez, R., Concepción, A. R., Nogueiras, C., Laguna, A., ... & Hernández, Y. (2009). Repair of UVB-damaged skin by the antioxidant sulphated flavone glycoside thalassiolin B isolated from the marine plant Thalassia testudinum Banks ex König. Mar. Biotechnol., 11, 74-80. http://dx.doi.org/10.1007/s10126-008-9123-8
Rodríguez, M., Tamayo, B. & Garateix, A. (2010). Los Organismos Marinos y los Cosméticos. Rev. Elec. Agen. Med. Amb., 19, 1-7.
Sánchez, F. (2006). Consideraciones sobre la capa de ozono y su relación con el cáncer de piel. Rev. Med. Chile, 134, 1185-1190. http://dx.doi.org/10.4067/s0034-98872006000900015
Seité, S., Fourtanier, A., Moyal, D. & Young, A. R. (2010). Photodamage to human skin by suberythemal exposure to solar ultraviolet radiation can be attenuated by sunscreens: a review. Brit. J. Dermatol., 163, 903-914. http://dx.doi.org/10.1111/j.1365-2133.2010.10018.x
SPSS. (2006). Statistical Package for the social science for Windows, version 15.0. Chicago, EE. UU.: SPSS Inc.
Svobodová, A., Psotová, J. & Walterová, D. (2003). Natural phenolics in the prevention of UV-¬induced skin damage. A review. Biomed., 147, 137-145. http://dx.doi.org/10.5507/bp.2003.019
Trautinger, F. (2001). Mechanisms of photodamage of the skin and its functional consequences for skin agening. Clin. Exp. Dermatol., 26, 573-577. http://dx.doi.org/10.1046/j.1365-2230.2001.00893.x
Zapata, O. & Mc Milan, M. (1979). Phenolic acid in seagrasses. Aquatic. Bot., 7, 307-317. http://dx.doi.org/10.1016/0304-3770(79)90032-9
Downloads
Published
How to Cite
Issue
Section
License
General terms and conditions
Revista Ciencias Marinas y Costeras by Universidad Nacional is located under a Licencia Creative Commons Atribución-NoComercial-SinDerivadas 3.0 Costa Rica.
The journal is hosted in open-access repositories such as the Repositorio Institucional de la Universidad Nacional, the Repositorio Kimuk de Costa Rica and la Referencia.
The editorial source of the journal must be acknowledged. For this purpose, use the doi identifier of the publication.
Self-archiving policy: The journal allows the self-archiving of articles in their refereed version, edited and approved by the Editorial Board of the Journal so that they are available in Open Access through the Internet. More information at the following link: https://v2.sherpa.ac.uk/id/publication/28915
