Covid-19 Vaccine Distribution: Combining SEIR and Machine Learning

Authors

DOI:

https://doi.org/10.15359/ru.36-1.12

Keywords:

SEIR, Machine Learning, Epidemic Model, Vaccination, Covid-19, El Salvador

Abstract

The purpose of this study is to build an epidemic model with vaccination control for Covid-19 in El Salvador. A combination of epidemiological SEIR (Susceptible, Exposed, Infectious or Recovered) models and the estimation of parameters using machine learning and contact networks is proposed. The project consisted of three phases: a) Analysis: the critical or key factors or variables of the phenomenon under study were identified, the model to be used, as well as its parameters and components, were defined, designed, and constructed b) Simulation: simulation made it possible to modify variables, implement alternatives, and modify the model itself without affecting the real system, which is highly useful for decision-making and preparing results and recommendations. The simulations were carried out using population data from El Salvador. c) Optimization: different scenarios were evaluated in which vaccination control measures and social distancing measures were applied, in order to identify the optimal strategy. As a result of this study, the best strategy for controlling the disease was identified: a combination of vaccinating the vulnerable population and maintaining social distancing measures provided the best results in terms of reducing the impact of infection and minimizing treatment costs. Finally, recommendations are made to government health authorities for distribution and application of the treatment.

References

Acuña Soto, R., Castañeda Dávila, L. & Chowell, G. (2011). A perspective on the 2009 A/H1N1 influenza pandemic in Mexico. Mathematical Biosciences and Engineering, MBE, 8(1), 223–238. https://doi.org/10.3934/mbe.2011.8.223

Argueta, C. E. (2020). El COVID-19 y el número reproductivo básico y efectivo en El Salvador: Una propuesta para su medición. FUNDAUNGO. https://www.fundaungo.org.sv/products/el-covid-19-y-el-numero-reproductivo-basico-y-efectivo-en-el-salvador-una-propuesta-para-su-medicion/492

Arino, J., Brauer, F. & den Driessche, P. (2018). A model for influenza with vaccination and antiviral treatment. Journal of theoretical biology, 253(1), 118–130. https://doi.org/10.1016/j.jtbi.2008.02.026

Brauer, F., Castillo-Chávez, C., Pava Salgado, E., & Barley, K. (2015). Modelos de la propagación de enfermedades infecciosas. Universidad Autónoma de Occidente. 10.13140/2.1.4882.5929

CDC. (2021). Diferentes vacunas contra el COVID-19. Centers for Disease Control and prevention. https://espanol.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines.html

Chowell, G., Ammon, C., Hengartner, N. & Hyman, J. (2006). Transmission dynamics of the great influenza pandemic of 1918 in Geneva, Switzerland: Assessing the effects of hypothetical interventions. Journal of theoretical biology 241(2), 193–204. https://doi.org/10.1016/j.jtbi.2005.11.026

Dal Molin Ribeiro, M.H., Gomes Da Silva, R., Cocco Mariani, V. & Dos Santos Coelho, L. (2020). Short-term forecasting COVID-19 cumulative confirmed cases: Perspectives for Brazil. Chaos, Solitons and Fractals. https://doi.org/10.1016/j.chaos.2020.109853

DIGESTYC. (2018). Encuesta de Hogares de Propósitos Múltiples 2018. Dirección general de estadística y censos. http://www.digestyc.gob.sv/index.php/novedades/avisos/869-ya-se-encuentra-disponible-la-publicacion-ehpm-2018.html

FMI. (2020). World economic outlook databases. International Monetary Fund. https://www.imf.org/en/Publications/SPROLLs/world-economic-outlook-databases#sort=%5C%40imfdate%5C descending

GOAL. (2021). ¿Cuánto cuesta la vacuna contra el COVID-19? https://www.goal.com/es-mx/noticias/cuanto-cuesta-vacuna-covid-19/1d0ngem2skf521hey98yr7shru

GOES. (10 de agosto, 2021). Datos diarios de COVID 19 en El Salvador. https://covid19.gob.sv/

Gómez Marín, J. (2020). Una hoja de ruta para la Vacuna COVID 19 en Colombia, un reto posible. Infectio. http://dx.doi.org/10.22354/in.v25i1.901

González-Melado, F., & Di Pietro, M. L. (2020). La vacuna frente a la COVID-19 y la confianza institucional. Enfermedades Infecciosas y Microbiología Clínica. https://doi.org/10.1016/j.eimc.2020.08.001

Herrera, M., Cruz, M. & Castillo-Chavez, C. (2011). Multiple outbreaks for the same pandemic: Local transportation and social distancing explain the different ‘waves’ of A-H1N1pdm cases observed in México during 2009. Mathematical biosciences and engineering: MBE, 8(1), 21–48. https://doi.org/10.3934/mbe.2011.8.21

Lenhart, S., & J. Workman. (2007). Optimal control applied to biological models.

McGee, S. (2021). SEIRS+ Model Framework. https://github.com/ryansmcgee/seirsplus/wiki

Nuño, M., G. Chowell, & C. Castillo-Chavez. (2007). On the role of cross-immunity and vaccines on the survival of less fit flu-strains. Theorical Population Biology 71(1), 20-29. https://doi.org/10.1016/j.tpb.2006.07.002

OPS. (2020). Fases de desarrollo de una vacuna. Organización Panamericana de la Salud. https://www.paho.org/es/documentos/covid-19-fases-desarrollo-vacuna

Piqueras, M., Cruz, Hortal Carmona, J. & Padilla Bernáldez, J. (2020). Visteme despacio que tengo prisa. Un análisis ético de la vacuna del COVID-19: fabricación, distribución y reticencia. Enrahonar. An International Journal of Theoretical and Practical Reason 65, 57–73. https://ddd.uab.cat/pub/enrahonar/enrahonar_a2020v65/enrahonar_a2020v65p57.pdf

Chimmula, R., Kumar, V. & Zhang, L. (2020). Time series forecasting of COVID-19 transmission in Canada using LSTM networks. Chaos, Solitons and Fractals, 135. https://doi.org/10.1016/j.chaos.2020.109864

Saralegui Vallejo, U. (2016). Modelos epidémicos con control por vacunación. https://www.researchgate.net/publication/322273233_Modelos_epidemicos_con_control_por_vacunacion

Thunström, L., Newbold, S., Finnoff, D., Ashworth, M., & Shogren, J. (2020). Beneficios y costos de usar el distanciamiento social para aplanar la curva de COVID-19. Journal of Benefit-Cost Analysis. http://ebour.com.ar/pdfs/Beneficios%20y%20costos%20de%20usar%20el%20distanciamiento%20social%20para%20aplanar%20la%20curva%20de%20COVID19.pdf

UNICEF. (2021). COVID-19 Vaccine Market Dashboard. https://www.unicef.org/supply/covid-19-vaccine-market-dashboard .

WHO. (2021). Draft landscape and tracker of COVID-19 candidate vaccines. https://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines.

Published

2022-01-31

Issue

Section

Original scientific papers (evaluated by academic peers)

Comentarios (ver términos de uso)

Most read articles by the same author(s)

1 2 3 4 5 6 7 8 9 10 > >>