Comparative tomographic and histological investigation of two biomaterials for preservation of the alveolar ridge

Authors

DOI:

https://doi.org/10.15359/ru.37-1.18

Keywords:

Dental biomaterials, bone grafts, bone substitutes, alveolar ridge preservation techniques

Abstract

[Objective] This investigation evaluates tomographic dimensional changes and histological changes after extraction with the use of two graft materials: Bio-Oss® xenograft and Bio-Gide® resorbable collagen membrane, and Puros® allograft and Biomed Extend® resorbable collagen membrane for the preservation of the alveolar ridge. [Materials and Methods] This is an experimental study in which 20-single tooth extractions were performed and two different biomaterials randomly assigned in two groups were compared. Members of Group A received xenograft-type material (Bio-Oss and Bio-Gide®), while members of group B received allograft-type material (Puros and Biomed®). Tomographic measurements were carried out on Day 0 and Day 210 after extraction. On Day 210 tissue samples were taken for histological analysis. [Results] Tomographic measurements did not show statistically significant variations except in the case of maximum width of the bone crest, which was smaller in the allograft group on day 210 with a value of p<0.05. Histological results show similarity between the two groups in cellular response, osteoid tissue, and mineralized new bone. Differences were observed in the amount of remaining material, with the highest presence of material found in the xenograft group. [Conclusion] The results of this study are similar to those found in the literature, and adequate preservation of the height and width of the bone ridge after an extraction was observed when xenograft or allograft bone substitute materials were employed, with very slight changes during the time of evaluation.

References

Aichelmann Reidy, M. E. y Yukna, R. A. (1998). Bone replacement grafts. Dental Clinics of North America, 42(3), 491-503. https://doi.org/10.1016/S0011-8532(22)00579-1

Araujo, M. G. y Lindhe, J. (2009). Ridge preservation with the use of Bio-Oss collagen: a 6-month study in the dog. Clinical Oral Implants Research, 20, 433-440. https://doi.org/10.1111/j.1600-0501.2009.01705.x

Araujo, M. G., Linder, E., Wennström, J. y Lindhe, J. (2008). The influence of Bio-Oss collagen on healing of an extraction socket: an experimental study in the dog. International Journal of Periodontics & Restorative Dentistry, 28, 123-135.

Barootchi, S., Wang, H., Ravidà, A. y Amor, F. (2019). Ridge preservation technique to avoid invasive bone reconstruction: A systematic review and meta-analysis: Naples Consensus Report Working. International Journal of Oral Implantology, 2(4), 399-416.

Becker, W., Urist, M., Becker, B. E., Jackson, W., Parry, D. A., Bartold, Vicenzzi, G., De Georges, D. y Niederwanger, M. (1996). Clinical and histologic observations of sites implanted with intraoral autologous bone grafts or allografts. 15 human case reports. Journal of Periodontology, 67, 1025-1033. https://doi.org/10.1902/jop.1996.67.10.1025

Cobos-Carbó, A. (2005). Ensayos clínicos aleatorizados (CONSORT). Randomized clinical trials (CONSORT), 125 (S1), 21-27. https://doi.org/10.1016/S0025-7753(05)72205-3

Froum, S., Cho, S., Rosenberg, E., Rohrer, M., y Tarnow, D. (2002). Histologic comparison of healing extraction sockets implanted with bioactive glass or demineralized freeze-dried bone allograft: A pilot study. Journal of Periodontology, 2(73), 94-102. https://doi.org/10.1902/jop.2002.73.1.94

Girón, J., Kerstner, E., Medeiros, T., Oliveira, T., Machado, G. M., Malfatt , C. F. y Pranke, P. (2021). Biomaterials for bone regeneration: an orthopedic and dentistry overview. Brazilian Journal of Medical and Biological Research, 54(9), 11055. https://doi.org/10.1590/1414-431x2021e11055

Iasella, J. M., Greenwell, H., Miller, R. L., Hill, M., Drisko, C., Bohra, A. A. y Scheetz, J. P. (2003). Ridge preservation with freeze-dried bone allograft and a collagen membrane compared to extraction alone for implant site development: A clinical and histologic study in humans. Journal of Periodontology, 74(7), 990-999. https://doi.org/10.1902/jop.2003.74.7.990

Kan, J. Y., Rungcharassaeng, K., Sclar, A. y Lozada, J. L. (2007). Effects of the facial osseous defect morphology on gingival dynamics after immediate tooth replacement and guided bone regeneration: 1-year results. Journal of Oral and Maxillofacial Surgery, 65, 13-19.

Lekovic, V., Camargo, P. M., Klokkevold, P. R., Weinlaender, M., Kenney, E. B., Dimitrijevic, B. y Nedic, M. (1998). Preservation of alveolar bone in extraction sockets using bioabsorbibles membranes. Journal of Periodontology, 69(9), 1044-1049. https://doi.org/10.1902/jop.1998.69.9.1044

Maiorana, C., Poli, P. P., Deflorian, M., Testori, T., Mandelli, F., Nagusky, H. y Vinci, R. (2017). Alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix. Journal of Periodontal & Implant Science, 47(4), 194-210.

https://doi.org/10.5051/jpis.2017.47.4.194

Manzini, J. (2000). Declaración de Helsinki: Principios éticos para la investigación médica sobre sujetos humanos. Acta Bioethica, 6(2). https://doi.org/10.4067/S1726-569X2000000200010

Oddó, P., Klein, C. y Contreras, A. (2020). Preservación alveolar post extracción en zona estética: Decisiones clínicas predecibles en sitio severamente afectado. International Journal of Interdisciplinary Dentistry, 13(1), 30-34. https://doi.org/10.4067/S2452-55882020000100030

Pauwels, R., Jacobs, R., Singer, S. R. y Mupparapu, M. (2015). CBCT-based bone quality assessment: are Hounsfield units applicable? Dentomaxillofacial Radiology, 44, 1-16. https://doi.org/10.1259/dmfr.20140238.

Schroop, L., Wenzel, A., Kostopoulos, L. y Karring, T. (2003). Bone healing and soft tissue contour changes following single-tooth extraction: a clinical and radiographic 12-month prospective study. International Journal of Periodontics & Restorative Dentistry, 23, 313-323.

Segnini, B., Borges Filho, F., Nicoli, L., Goncalves, M., Marcantonio, C., Oliveira, G. y Marcantonio, E. Jr. (2021). Impact of soft tissue graft on the preservation of compromised sockets: a randomized controlled clinical pilot study. Acta odontológica Latinoamericana, 34 (2), 119-126. https://doi.org/10.54589/aol.34/2/119.

Troiano, G., Zhurakivska, K., Lo Muzio, L., Laino, L., Cicciu M., y Russo L. (2018). Combination of bone graft and resorbable membrane for alveolar ridge preservation: A systematic review, meta-analysis, and trial sequential analysis. Journal of Periodontology, 89, 6-57.

Vargas, L., Serrano, C. A. y Estrada, J. H. (2012). Preservación de alvéolos postexodoncia mediante el uso de diferentes materiales de injerto. Revisión de la literatura. Universidad de Odontología, 31(66), 145-183.

Zhao, R., Yang, R., Cooper, P. R., Khurshid, Z., Shavandi, A. y Ratnayake, J. (2021). Bone Grafts and Substitutes in Dentistry: A Review of Current Trends and Developments. Molecules, 26(10), 3007. https://doi.org/10.3390/molecules26103007

Published

2023-06-22

Issue

Section

Original scientific papers (evaluated by academic peers)

Comentarios (ver términos de uso)

Most read articles by the same author(s)

1 2 3 4 5 6 7 8 9 10 > >>